Horses with Cushing’s produce excessive amounts of cortisol from their adrenal glands


Cortisol has many functions in the body including maintaining blood pressure, modifying the body’s inflammatory immune response, regulating the function of nervous tissue, regulating muscle tone and connective tissue repair, and regulating the breakdown of carbohydrates, proteins, and fats by controlling insulin levels in the body. The excessive amount of cortisol produced in horses with Cushing’s disease leads to many problems including recurring laminitis, muscle atrophy, susceptibility to disease, slow wound healing, excessive hair growth along with failure to shed, and lethargy.